The Hope Laboratory
 
 

Lab Publications

 

  • Baines, K.N., Ferreira, C., Hopkins, P.M., Shaw M.A. and Hope, I.A. "Aging Effects of Caenorhabditis elegans Ryanodine Receptor Variants Corresponding to Human Myopathic Mutations." G3: Genes, Genomes, Genetics, 7, 1451-61, (2017).
  • Savory, F.R., Benton, T.G., Varma, V., Hope, I.A. and Sait, S.M. "Stressful environments can indirectly select for increased longevity." Ecol. Evol., 4, 1176-85, (2014).
  • Craig, H., Wirtz, J., Bamps, S., Dolphin, C.T. and Hope, I.A. "The significance of alternative transcripts for Caenorhabditis elegans transcription factor genes, based on expression pattern analysis." BMC Genomics, 14, 249, (2013).
  • Feng H. and Hope, I.A. "The Caenorhabditis elegans homeobox gene ceh-19 is required for MC motorneuron function." Genesis: The Journal of Genetics and Development, 51, 163-78, (2013).
  • Hirani, N., Westenberg, M., Gami, M.S., Davis, P., Hope, I.A. and Dolphin, C.T. "A simplified counter-selection recombineering protocol for creating fluorescent protein reporter constructs directly from C. elegans fosmid genomic clones." BMC Biotechnology, 13, 1, (2013)
  • Feng, H., Reece-Hoyes, J.S., Walhout, A.J.M. and Hope, I.A. "A regulatory cascade of three transcription factors in a single specific neuron, DVC, in Caenorhabditis elegans." Gene, 494, 73-84, (2012).
  • Feng, H., Craig, H.L. and Hope, I.A. "Expression pattern analysis of regulatory transcription factors in Caenorhabditis elegans." in "Gene Regulatory Networks" Methods in Molecular Biology, 786, 21-50, (2011).
  • Savory, F.R., Sait, S.M. and Hope, I.A. "DAF-16 and delta-9 Desaturase Genes Promote Cold Tolerance in Long-Lived Caenorhabditis elegans age-1 Mutants." PLoS One, 6(9), e24550, (2011).
  • Boyle, J. H., Berri, S., Tassieri, M., Hope, I. A. and Cohen, N. "Gait modulation in C. elegans: It's not a choice, it's a reflex!" Frontiers in Behavioral Neuroscience, 5, 10, (2011).
  • Bamps, S., Wirtz, J. and Hope, I.A. "Distinct mechanisms for delimiting expression of four Caenorhabditis elegans transcription factor genes encoding activators or repressors." Molecular Genetics and Genomics, 286, 95-107, (2011).
  • SchusterE. , McElwee, J.J., Tullet, J.M.A., Doonan, R., Matthijssens, F., Reece-Hoyes, J.S., Hope, I.A., Vanfleteren, J.R., Thornton, J.M. and Gems, D. "DamID in C. elegans reveals longevity-associated targets of DAF-16/FoxO." Molecular Systems Biology, 6, 399, (2010).
  • Westenberg, M., Bamps, S., Soedling, H., Hope, I.A. and Dolphin, C.T. "Escherichia coli MW005: lambda Red-mediated recombineering and copy-number induction of oriV-equipped constructs in a single host." BMC Biotechnol., 10, 27, (2010).
  • Ghosh, S. and Hope, I.A. "Determination of the mobility of novel and established Caenorhabditis elegans sarcomeric proteins in vivo." Eur. J. Cell Biol., 89, 437-48, (2010).
  • Bamps, S., Wirtz, J., Savory, F., Lake, D. and Hope, I.A. "The Caenorhabditis elegans sirtuin gene, sir-2.1, is widely expressed and induced upon caloric restriction." Mech. Aging Development, 130, 762-70, (2009).
  • Berri, S., Boyle, J.H., Tassieri, M., Hope, I.A. and Cohen, N. "Forward locomotion of the nematode C. elegans is achieved through modulation of a single gait." HFSP J., 3, 186-93, (2009).
  • Bamps, S. and Hope, I.A. "Large-scale gene expression pattern analysis in situ in Caenorhabditis elegans." Briefings in Functional Genomics and Proteomics, 7, 175-83, (2008).
  • Dupuy, D., Bertin, N., Hidalgo, C.A., Venkatesan, K., Tu, D., Lee, D., Rosenberg, J., Svrzikapa, N., Blanc, A., Carnec, A., Carvunis, A.-R., Pulak, R., Shingles, J., Reece-Hoyes, J., Hunt-Newbury, R., Viveiros, R., Mohler, W.A., Tasan, M., Roth, F.P., Le Peuch, C., Hope, I.A., Johnsen, R., Moerman, D.G., Barabasi, A.-L., Baillie, D. and Vidal, M. "Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans." Nature Biotechnology, 25, 663-8, (2007).
  • Reece-Hoyes, J.S., Shingles, J., Dupuy, D., Grove, C.A., Walhout, A.J.M., Vidal, M. and Hope, I.A. "Insight into transcription factor gene duplication from Caenorhabditis elegans Promoterome-driven expression patterns." BMC Genomics, 8, 27, (2007).
  • Deplancke,B., Mukhopadhyay, A., Ao, W., Elewa, A.M., Grove, C.A., Martinez, N.J., Sequerra, R., Doucette-Stamm, L., Reece-Hoyes, J.S., Hope, I.A., Tissenbaum, H.A., Mango, S.E. and Walhout. A.J.M. "A Gene-Centered C. elegans Protein-DNA Interaction Network." Cell, 125, 1193-205, (2006).
  • Dolphin, C.T. and Hope, I.A. "Caenorhabditis elegans reporter gene fusion genes generated by seamless modification of large genomic DNA clones." Nucleic Acids Research, 34, e72, (2006).
  • Reece-Hoyes, J.S., Deplancke, B., Shingles, J., Grove, C.A., Hope, I.A. and Walhout, A.J.M. "A Compendium of C. elegans Regulatory Transcription Factors: A Resource For Deciphering Transcription Regulatory Networks." Genome Biology, 6, R110, (2005).
  • D. Dupuy, Q. Li, B. Deplancke, M. Boxem, T. Hao, P. Lamesch, R. Sequerra, S. Bozak, L. Doucette-Stamm, I.A. Hope, D.E. Hill, A.J.M. Walhout and M. Vidal. "Caenorhabditis elegans Promoterome 1.1: a Gateway to Localizome Projects." Genome Research. 14, 2169-75, (2004).
  • I.A. Hope, J. Stevens, A. Garner, J. Hayes, D.L. Cheo, M.A. Brasch and M. Vidal. "Feasibility of genome-scale construction of promoter::reporter gene fusions for expression in Caenorhabditis elegans using a MultiSite Gateway recombination system." Genome Research. 14, 2070-5, (2004).
  • P.J. Appleford, M.Griffiths, S.Y.M. Yao, A.M.L. Ng, E.G. Chomey, R.E. Isaac, D. Coates, I.A. Hope, C.E. Cass, J.D. Young and S.A. Baldwin. "Functional redundancy of two nucleoside transporters of the ENT family (CeENT1, CeENT2) required for development of Caenorhabditis elegans." Molecular Membrane Biology. 21, 247-60, (2004).
  • I.A.Hope, A. Mounsey, P. Bauer and S. Aslam. "The forkhead gene family of Caenorhabditis elegans." Gene, 304, 43-55, (2003).
  • T.Inoue, D. R.Sherwood, G.Aspöck, J.A.Butler, B.P.Gupta, M.Kirouac, M.Wang, P.-Y.Lee, J.M.Kramer, I.Hope, T.R.Bürglin and P.W.Sternberg. "Gene expression markers for C. elegans vulval cells." Mechanisms of Development, 119, Supplement 1, S203-S209, (2002).
  • A.Mounsey, P.Bauer, I.A.Hope. "Evidence suggesting that a fifth of annotated Caenorhabditis elegans genes may be pseudogenes." Genome Research, 12, 770-5, (2002).
  • I.A.Hope."Broadcast Interference -Functional genomics." Trends in Genetics, 17, 297-9, (2001).
  • I. A.Hope. "RNAi surges on: application to cultured mammalian cells." Trends in Genetics, 17, 440, (2001).
  • I.A.Hope. Chapter 5, "Embryology, Developmental Biology and the Genome.", pp. 121-145. In 'The Biology of Nematodes.' ed. D.L.Lee. publ. Harwood Academic Publishers, Reading.
  • L.Molin, A.Mounsey, S.Aslam, P.Bauer, J.Young, M.James, A.Sharma-Oates, and I.A.Hope. "Evolutionary conservation of redundancy between a diverged pair of forkhead transcription factor homologues." Development, 127, 4825-4835, (2000).
  • Molin, L., Schnabel, H., Kaletta, T., Feichtinger, R., Hope, I.A., and Schnabel, R. "Complexity of developmental control: Analysis of embryonic cell lineage specification in Caenorhabditis elegans using pes-1 as an early marker." Genetics 151, 131 - 141, (1999).
  • Hope, I.A.(ed.) "C. elegans: A Practical Approach" The Practical Approach Series, Oxford University Press, (1999).
  • Mounsey, A., Molin, L., and Hope, I.A. "Chapter 9: Gene expression patterns." in: "C. elegans: A Practical Approach", The Practical Approach Series, Hope, I.A.(ed), Oxford University Press: 181 - 199 (1999)
  • Cove, D.J., Hope, I.A. and Quatrano, R.S. (1999). "Polarity in Biological Systems." (Chapter 32, pp507-24) in 'Development. Genetics, epigenetics and environmental regulation.' ed. V.E.A.Russo, D.J.Cove, L.G.Edgar, R.Jaenisch and F.Salamini. publ. Springer, Berlin.
  • Hope, I.A., Arnold, J.M., McCarroll, D., Jun, G., Krupa, A.P., and Herbert, R. "Promoter trapping identifies real genes in C. elegans." Molecular and General Genetics 260, 300 - 308, (1998).
  • Hope, I.A., Albertson, D.G., Martinelli, S.D., Lynch, A.S., Sonnhammer, E., and Durbin, R. "The C. elegans expression pattern database: a beginning." Trends in Genetics 12(9), 370-1, (1996)
  • MacGregor, D., Hope, I.A. and Isaac, R.E.. (1995) "Neurobiology and Development of Nematodes." in a single volume 'Encyclopedia of molecular biology and molecular medicine.' ed. R.A.Meyers, publ. VCH, Weinheim.
  • Hope, I.A. "The Caenorhabditis elegans approach to genome analysis." J. Med. Genet. 32, 136, (1995).
  • Lynch, A.S, Briggs, D. and Hope, I.A. "Developmental expression pattern screen for genes predicted in the C. elegans genome sequencing project." Nature Genetics 11, 309-13, (1995).
  • Hope, I.A. "PES-1 is expressed during early embryogenesis in Caenorhabditis elegans and has homology to the fork head family of transcription factors." Development 120, 505 - 514 (1994)
  • Hope, I.A. (1994) "Genetic transformation of Caenorhabditis elegans." in 'The genetics of entomopathogenic nematode bacterium complexes.' ed. Burnell,A.M., Ehlers,R.-U. and Masson,J.-P. Published by the EC (proceedings of a meeting), pp14-22, EUR 15681 EN.
  • Hope, I.A. "Caenorhabditis elegans, the Nematode Worm". Book Chapter in :"Embryos. Color Atlas of Development" J. Bard (ed), Wolfe Publishing, London, England. : 55 - 75, (1994)
  • Young, J.M. and Hope, I.A. "Molecular markers of differentiation in Caenorhabditis elegans obtained by promoter trapping." Developmental Dynamics 196, 124 -132 (1993)
  • Hope, I.A. "Promoter trapping in Caenorhabditis elegans." Development 113, 399 - 408 (1991)

     

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